Nicotinamide adenine dinucleotide (oxidized form, NAD+) is a critical coenzyme, with functions ranging from redox reactions and energy metabolism in mitochondrial respiration and oxidative phosphorylation to being a central player in multiple cellular signalling pathways, organ resilience, health, and longevity.

“NAD+ IV Therapy: Rejuvenate Your Energy, Brain, and Body”

NAD+ IV therapy is a revolutionary treatment designed to restore cellular health, enhance brain function, and promote longevity. Discover how NAD+ can help you feel energized, focused, and revitalized.

Benefits of NAD+ IV (intravenous applications)

Beta NAD+ (β-Nicotinamide adenine dinucleotide) is a crucial coenzyme involved in numerous cellular processes, particularly oxidation-reduction reactions where it acts as an electron carrier. It exists in two forms: NAD+ (the oxidized form) and NADH (the reduced form), which together constitute a redox pair. NAD+ is essential for various metabolic pathways like glycolysis, the Krebs cycle, and oxidative phosphorylation, as well as for DNA repair and other cellular functions. 

Therefore, it helps cells do things like make energy, fix damaged DNA, and produce genes. It has gotten a lot of attention because it might slow down aging and be good for your health in general. NAD+ is an electron transporter when it is reduced, while NADH takes electrons to the mitochondria, where they are used to make energy.

NAD+ levels can go down with age and other things, making less energy and making things work less well. Increasing NAD+ levels may be good for your health as a whole and may even slow down the aging process.

NAD+ is believed to support mitochondrial function, DNA repair, and overall cellular health. But study is still being done in this area, so the full range of NAD+'s benefits and how it works are not yet known. Sirtuins, which control how cells work, need NAD+ as a cofactor to do their jobs. Supplements with NAD+ precursors such as nicotinamide riboside (NR) or nicotinamide mononucleotide (NMN) are becoming popular for raising NAD+ levels.

Sirtuins are a family of signalling proteins involved in metabolic regulation. They are a type of protein involved in regulating cellular processes including the ageing and death of cells and their resistance to stress.

Types of NAD+ treatments:

• Nasal
  
• Topical
  
• Oral
  
• Intravenous
• and innovative applications

How suitable is the NAD+ application:

The newly developed NAD+ treatment has shown promise in better health and fighting some problems that come with getting older. Yet, for NAD+ treatment to work well, it is important to know who can gain the most from it.

Age-related decline and cellular energy:

As we age, NAD+ levels decrease, affecting cellular energy production. By restoring NAD+ levels, speeding up the metabolism, and turning back the signs of aging, NAD+ treatment can improve energy, physical ability, and mental function.

Neurodegenerative diseases and cognitive decline:

Neurodegenerative diseases like Alzheimer's, Parkinson's, Multiple sclerosis, and similar conditions may lead to memory loss and problems with the way the brain and nervous system work. NAD treatment helps repair cells, lowers inflammation, and improves the health of neurons. This slows the progression of disease and makes it easier to think.

Chronic fatigue and mitochondrial disfunctions:

Chronic fatigue syndrome and mitochondrial dysfunction impact quality of life. NAD+ treatment speeds up the metabolism and improves the way the mitochondria work. This gives people with these conditions more energy and less tiredness.

Substance abuse and addiction recovery:

NAD+ treatment aids substance abuse and addiction recovery by reducing cravings, minimizing withdrawal symptoms, and enhancing detoxification. It restores neurotransmitter balance, optimizes brain function, and reduces relapse risk.

Age-related eye conditions:

Age-related macular degeneration (AMD) and other ocular conditions impact vision and daily activities. Treatment with NAD+ helps keep the eyes healthy by protecting retinal cells, lowering oxidative stress, and improving the function of mitochondria. Individuals can explore NAD therapy as an adjunctive treatment option.

NAD actions in the body:

• Energy production at the cellular levels
• ATP production and recovery support
• Anti-aging effects and longevity
• Addiction recovery support by replenishing depleted neurotransmitters, enhancing cellular energy, and reducing craving
• Degeneration and disease recovery
• Eyesight improvements mainly due to aging

NAD contraindications:

• Seizure
• Allergies to NAD+
• Arrhythmia
• Palpitations
• Hypertensive crisis
• Thyroid diseases
• Nitrogen overload (AKA azotemia or uremia, refers to an excess of nitrogenous waste products in the blood, often due to kidney problems)
• Chronic Renal insufficiencies
• CLD (chronic liver diseases)
• Patients below age 18
• Pregnancy & Breastfeeding
• Alcohol intoxication
• Active bleeding (ongoing menses)
• Acute trauma to the head

Intravenous NAD side effects:

Even though NAD IV therapy is usually safe and well-tolerated, it's important to know what side affects you might feel during treatment. They may include:

• Flushing and warm sensation (which causes the skin to turn red and feel warm all at once. This effect results from the rapid release of prostaglandins, which dilate blood vessels)
• Nausea and GI (gastrointestinal) disturbances (During or after NAD IV treatment, some people may feel a little bit sick, have stomach pain, or have problems with their gastrointestinal tract. These effects are usually temporary and resolve without medical intervention. Maintaining adequate hydration and adjusting the infusion rate can help cut these symptoms)
• Tightness in the chest area and dizziness while under the IV (the sensation of chest tightness is seen in people who receive larger doses of NAD intravenously. It is not dangerous, and people should remain calm and relax. By lowering the applied dose or slowing the drips, the tightness goes away. About dizziness, although rarely, some people who get NAD IV therapy may feel that temporarily or could even faint during or after the treatment. Most of the time, these signs are mild and go away quickly. During the shot, you should make sure you're in a comfortable, relaxed position and let the person treating you know if you're in pain)
  

Doses of NAD+ IV Therapy: